HOMEOSTASIS

ANTICONVULSANT THERAPY-INDUCED ALTERATIONS IN CALCIUM HOMEOSTASIS

35 epileptic patients, aged 10 to 58 years (mean 23), who were taking anticonvulsant drugs were studied. The patients exhibited a 34% reduction in serum calcium levels, a 41 % increase in serum alkaline phosphatase activity and a slight but insignificant decrease in serum phosphate, compared to untreated controls. These changes appear to be related to the anticonvulsant drug taken, in the ...

REGULATION OF ACID-BASE HOMEOSTASIS BY THE KIDNEY

anticonvulsant therapy-induced alterations in calcium homeostasis

35 epileptic patients, aged 10 to 58 years (mean 23), who were taking anticonvulsant drugs were studied. the patients exhibited a 34% reduction in serum calcium levels, a 41 % increase in serum alkaline phosphatase activity and a slight but insignificant decrease in serum phosphate, compared to untreated controls. these changes appear to be related to the anticonvulsant drug taken, in the follo...

Epithelial Homeostasis

Epithelia form intelligent, dynamic barriers between the external environment and an organism's interior. Intercellular cadherin-based adhesions adapt and respond to mechanical forces and cell density, while tight junctions flexibly control diffusion both within the plasma membrane and between adjacent cells. Epithelial integrity and homeostasis are of central importance to survival, and mechan...

Updating Homeostasis

10 years ago, a group of us put on an international meeting at the NIH entitled “The Energetic and Dynamic Basis of Health and Aging” [3]. The centerpiece of our conference was the reification of the term homeodynamics [4]. This word was proposed and elaborated by Dr. Gene Yates of UCLA who was a leader of our conference. Homeodynamics extends homeostasis into a more inclusive term. It is evide...